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Rafail Tasakis

Life sciences and deep tech venture investor building commercial strategy from technical first principles

Antwerp, BelgiumActively looking

I am a scientifically trained entrepreneur focused on early-stage venture capital for deep tech and life sciences. With a PhD in bioinformatics and cancer biology, I read data rooms and technical claims with equal fluency, so I can underwrite technical risk that many generalists miss. Since 2024, I have contributed to investment and portfolio processes valued at $127.9M. I have supported ventures across immunotherapy, gene therapy, and planetary health by facilitating commercial pivots, advancing TRL derisking models, and advising derisking and commercialization roadmaps, including work tied to a $20M portfolio value, €7.5M in segment value, and €2.5M in financing. After crossing from research into business, I have built commercial functions from scratch, led cross-functional teams, and run technical due diligence and M&A validations. In my previous role, I managed consulting delivery for an acquisition valued at $95M and helped grow partnerships, proposals, and go-to-market execution that added $1.5M in value. Currently I am a Founder and Principal Consultant with an advisory practice that helps deep tech and life sciences teams manage innovation, financing, and derisking go-to-market roadmaps, while I complete a part-time Executive MBA at Antwerp Management School.

Experience

TV

Founder & Principal Consultant

Takasakis Venture Strategy

Oct 2025 – Present

Antwerp, Belgium

Led business development for a tech-driven immunotherapy scale-up, facilitating a commercial pivot from therapeutics to a solution-driven model using native AI/ML IP (portfolio value: $20M). Built a derisking framework for VIB Grand Challenges by advancing TRL through co-creation models in the planetary health portfolio (segment value: €7.5M). Served on the External Advisory Board of TextaDNA and advised on derisking/commercialization roadmaps, while advising Enthecis on fundraising strategy and co-founding Bench2Ventures to train scientists to think like founders.

Business developmentCommercial pivotNative AI/ML IPDerisking frameworkTRL advancementCo-creation modelsVenture strategyExternal advisory boardDerisking and commercialization roadmapFundraising strategyPartnershipsGo-to-market strategyFounder education / ecosystem building
S

Head of Business Development

Solvuu

Aug 2024 – Sep 2025

New York, United States

Managed a cross-functional team of four and led consulting delivery for key clients, including technical due diligence on assets during an acquisition valued at $95M. Drove business growth by building partnerships, developing winning proposals (NYU Endless Frontiers Labs), and managing marketing, sales, and account operations, delivering $1.5M in value added. Co-shaped company strategy and product/service development alongside the CEO/CSO and elevated brand visibility through public engagements and ecosystem outreach.

Business developmentCross-functional team leadershipTechnical due diligenceM&A validationPartnership buildingProposal developmentConsulting deliveryMarketingSalesAccount operationsStrategy and product/service developmentPublic engagementsEcosystem outreach
IS

Bioinformatics Scientist

Icahn School of Medicine at Mount Sinai

Jul 2023 – Jul 2024

New York, United States

Delivered consulting services to early-stage drug-discovery ventures, driving agile project execution and advising client leadership to support technical and commercial success. Supported business growth through lead generation, client engagement, and drafting/closing statements of work (SoWs), contributing to a significant revenue stream.

ConsultingAgile project executionClient advisoryLead generationClient engagementStatements of work (SoWs)Business development
IS

Postdoctoral Researcher

Icahn School of Medicine at Mount Sinai

Jan 2022 – Jul 2023

New York, United States

Conducted translational research on chemotherapy and CAR-T resistance in 1,500 multiple myeloma patients using real-world evidence and genomic big-data analytics. Contributed to federal grant applications through data generation and writing support, translating analytical findings into fundable research narratives.

Translational researchChemotherapy researchCAR-T resistanceReal-world evidence (RWE)Genomic big data analyticsData generationGrant writingScientific communication
GC

Doctoral Researcher

German Cancer Research Center (DKFZ)

Aug 2017 – Dec 2021

Heidelberg, Germany

Built and validated bioinformatics pipelines for human and mouse models to elucidate genomic changes associated with cancer relapse in both hematological and solid tumors. Led data management and analytics for a 23-scientist department and coordinated analytics across five international collaborations, ensuring reliable, reproducible analysis outputs for downstream research decisions.

Bioinformatics pipelinesData validationHuman/mouse modelsGenomic analysisCancer relapse analyticsMulti-omics analysisData managementData analytics leadershipInternational collaborationReproducible analytics
EM

Visiting Scientist in Bioinformatics

European Molecular Biology Laboratory (EMBL)

Sep 2016 – Aug 2017

Heidelberg, Germany

Trained in bioinformatics and big data analytics, building foundational skills for downstream genomic and translational research work. Focused on practical analytics approaches to support large-scale biological data interpretation.

BioinformaticsBig data analyticsGenomic analytics foundationsData interpretation

Education

AM
Antwerp Management School

Executive MBA (candidate)

Oct 2025 – Jun 2027

Currently half-way through a part-time Executive MBA; expected graduation June 2027.

UO
University of Heidelberg, Germany

Doctor of Natural Sciences (PhD)

Aug 2017 – Nov 2021

Magna Cum Laude

AU
Aristotle University of Thessaloniki, Greece

Bachelor of Science in Biology, Biology

Oct 2012 – Sep 2016

First-class Honors

Skills

Investment & Financial AnalysisCommercial & Business DevelopmentFinancial modeling and valuationInvestor relationsStrategic partnershipsFundraisingBusiness due diligenceDeal sourcingPortfolio managementGo-to-market strategyUSP and brand positioningMarket and competitive landscapingRisk analysisProduct and IP managementCommunication & stakeholder engagementScientific communicationPublic speakingBioinformaticsMulti-omics analysisMolecular and cellular biologyGeneticsBiomedical translationTechnology feasibility assessmentAI-augmented research, analysis & opsHPC/cloud computingData analytics and visualizationProgrammingMicrosoft & Google productivity suitesInvestor narrative developmentC-suite engagement

Languages

English
Native or bilingual proficiency
Greek
Native or bilingual proficiency
Dutch
German