Seae Ventures

Founded over 20 years ago, Kaiser Permanente Ventures has developed into a national leader in strategic venture investing in healthcare. In partnership with Kaiser Permanente and our limited partners, the KPV team has invested in and helped support over 65 companies, representing some of the most important innovations in healthcare delivery over this time period. We’ve achieved these successes through deep engagement within KP and across our investment partners, leveraging the tremendous insights that come from those leading our healthcare systems and care delivery to identify the most pressing needs within healthcare and select the innovations that most effectively address those opportunities. Together with our partners, KP and KPV represents22,000+ clinicians and over 180,000 healthcare employees 38+ acute care hospitals and over 600 other healthcare-related facilities Approximately $65 billion in annual operating revenue Largest U.S. single comprehensive electronic medical record system Leading evidence-based care delivery mode Our fund targetsHealth Information Technology (Enterprise Solutions) Digital Health Healthcare Services Medical Devices Diagnostics and Precision Medicine

Pureland Global Venture is a direct investment fund and part of the Pureland Group which targets impact investment deals in the medical technology sector. We are Singapore-based with a focus in APAC, India and the US. The fund deals with early-stage companies who have potential to inject value into the patient care system, save lives and reduce gaps in the supply and demand chains. Since we were established, we have invested in multiple medical sectors in both medical devices and ML-based solutions. MISSION - WHAT WE WANT TO ACHIEVE Established with the goal of giving people access to healthcare and also providing them with clinical choices, our mission is to bring medical solutions and savings to 100 million people around the world. We strongly believe in people who don’t just care about profit and who want to make the world a better place by solving real issues and pushing forward the latest evolution in medical technology. We envision bringing together impactful start-ups, commercial partners, insightful advisors and clinical providers in order to build a sustainable foundation for affordable, accessible and high-quality healthcare. WHY HEALTHCARE? Worldwide healthcare spending is expected to continue to rise at an alarming rate with a slight difference in some countries. Of all the leading factors, life expectancy appears to still be on the rise. By 2050, 1/6 people in the world will be over the age of 65 (16%), an increase from 1/11 in 2019 (9%). The number of people aged over 80 is projected to be 426 million by 2050 according to the United Nations population prospects. As we are entering a smart-health generation, the ecosystem demands more cost-effective solutions and appropriate treatments which can be delivered at the appropriate time and location. Clinicians use technology to give more holistic solutions to an aging population and provide more accurate diagnostics. Care delivery stakeholders use data and communicate more effectively and efficiently. Patients are involved in their own treatment plans and more healthcare access is delivered to people who did not previously have access. Unfortunately, we still face issues such as the increasing cost of healthcare, aging population, limited resources and shortages of healthcare professionals in various parts of the world. In order to combat these problems, government support and spending alone is not enough. We believe that these shortages can be filled by technology, which can be our solution for ensuring sufficient healthcare for future generations. This is also the reason why we are keen on enterprises which can provide solutions to combat these issues and create positive changes in the smart-health era. Founded in Singapore, we hope to be able to leverage the geographical advantage of Asia, and put together growth opportunities for these technologies which will make them accessible globally in the long term. WE SUPPORT START-UPS POST INVESTMENTFOUNDER SUPPORT: Start-ups regularly face critical decision-making as businesses grow from continuous market feedback and unexpected situations. We understand how difficult it can be and we will work together with the founders as a team in order to assist them with scaling their company, whether from networking referrals at the R&D stage, business strategy improvement at the growth stage, or EBITDA optimisation at a later stage. We offer support to founders for the optimisation of team structure as their businesses grow so they can overcome challenges and compete globally. MANUFACTURING SUPPORT: Manufacturing is one of the most crucial aspects of any device company, but it is often where mistakes are made. We advise our companies who experience manufacturing challenges from prototyping to mass production. In order to achieve this, we provide strategic value to our portfolio companies by connecting them to cost-effective manufacturing partners throughout the plastic, PCBA, silicon/rubber and final assembly industries. Our partners are high-mix and low-volume suppliers who understand the challenges of start-ups. Outside of production, we assist companies with lower case costing, set-up and management. GOVERNANCE: Establishing a good corporate culture and necessary internal control will mitigate business losses from major risks and lay the foundations for a company to improve. In a later stage funding cycle, correct corporate governance and internal control are paramount before larger funds buy into the company’s vision and growth story. We have a complete understanding of control and our networks are comprised of global experts in financial knowledge and risk assurance who can work together with our companies. FUNDRAISING: We typically fund companies while they are still young, from their seed to their series A round. Given the heavy research and development nature of medical technology companies, they usually require additional funding in order to boost their business quickly. Post-investment, we will not only collaborate on budgets and milestone adjustments but will more importantly offer assistance with financial modeling and revenue projection. This ensures that companies gain a higher chance of future investment. Finally, we work with other larger funds all over the world who specialise in revenue growth in order to understand their needs when they select their investment targets. EXIT: We seek founders with longer-term goals and a desire to take their companies to global players. Given our evergreen nature and flexible exit strategy, we are well suited to the long operation cycle of healthcare companies. At the same time, we understand and respect that some founders have a shorter term goal of M&A to boost market shares, expand business services or leverage bigger players to scale the company. We are experienced in company buy-out considerations and offer our support to founders as long as the company fits within our investment mandate.

Canada’s leading digital healthcare Venture Capital firm, offering local depth with global reach. We are healthcare practitioners, operators and founders with over 100 years’ experience and a deep network. We focus on early stage and high-growth companies shaping the future of healthcare delivery and empowering them to scale and grow. How We InvestStage: Investments will be in early stage companies ranging from pre-Seed rounds through pre-IPO with initial investments focused on Seed and Series A rounds Areas: We look for groundbreaking HealthTech ideas focusing on digitization of healthcare, emergence of consumer MedTech, and consumerization of health and wellness Locations: We invest primarily in companies located in Canada, the US and Israel that target markets in North America and Europe

We believe that these solutions cover a wide spectrum that includes the optimization of physical, mental, social and financial wellness, serving as the core components that will undergird the conscious, communal shift toward a healthier future. Our primary goal is to empower passionate founders who develop innovative ideas that impact all bodies. We're investing in more than just potential, we’re doubling down on the endless realm of human potential. With efficiency in mind, we like to spend our first meeting getting to understand the founder(s) first. Your first conversation may be with one of our Partners or investors. Each member of our team has a voice and it's respected at the table. After that conversation, we huddle to connect the dots, reflect on your story and think. From there we spend time with information shared and will come back with deeper questions that move the relationship forward. These are not questions to occupy your inbox, but questions formulated on our path to deep conviction. HEALTH Healthcare has reached an inflection point. The landscape is rapidly shifting towards value based care, deep personalization, and an endless appetite for connected data that will forever change the way we communicate with health providers, our families and ourselves. WELLNESS The wellness industry is a $4.5T opportunity, as more consumers seek to reduce their healthcare costs while exploring ways to be healthier and happier across physical, mental, social and spiritual dimensions of their lives. We seek innovative companies using technology to deliver benefits that are meaningful, measurable and scalable. TECHNOLOGY Software will continue to impact the world in ways never imagined. We're firm in our belief of embracing technology as the conduit for optimization. Innovative applications and connected hardware will continue to change behaviors, augment processes and provide stable infrastructure to advance the world's capabilities. STAGE & CHECK SIZE Our funding decisions are made by consensus. There will always be an internal deal champion that will serve as your lead investor. We practice a rigorous diligence process that can sometimes be complex or very swift - but we typically are able to gather the information we need in 2 weeks or less, once we've aligned on our potential partnership. It's our obligation to earn your trust and build on our relationship. To that end we run a transparent process, with no "GOTCHA" moments. We will work closely with the founder(s) to determine our entry point that makes sense. We are hands-on investors, we set out with a 90 day action plan to be additive at the outset. Stage: Seed-Series A Size: $500K-$3MM Fund Size: $50M As the capital landscape continues to evolve, we remain flexible to understand the specific needs of the entrepreneur. We have a framework that directs our investing. In order for us to spend dedicated time with our founders, we target 6-8 investments per year. These companies typically have a working prototype product getting user feedback or generating revenue, approaching product market fit. On occasion, we invest in exceptional teams at the concept level.

At the foundation of each of our investments is a commitment to helping our portfolio companies grow so they can better serve employers of all size. Employers make significant investments to make health care more accessible and easier to navigate. Our portfolio companies bring innovations to market that meet some of employers’ most pressing health care needs, including care navigation, advanced primary care, fertility planning and advanced analytics. Here are some of our current key areas of focus: Drug Management: Prices for drugs – particularly in high-cost categories like oncology, obesity and cell gene therapy – are outpacing inflation. We seek investment opportunities that address drug spend and access, with a specific focus on high-cost drugs or conditions that are highly prevalent in employer-sponsored insurance populations. Data and Analytics: Employers need solutions that make the vast amount of available health care data actionable and tailored to their insured populations. As such, we consider investment opportunities that provide the necessary infrastructure and analytic capabilities to impact administrative efficiency or drive improvements in health care quality and price transparency. Small- and Medium-Sized Business (SMB) Solutions: Rising health care costs place a severe burden on SMBs. In fact, the smallest employers are facing the biggest hikes in premium costs. Employers with just 1-10 employees saw a 12% increase in average family plan premiums in 2022. To help navigate this challenge, we weigh investment opportunities that enable SMBs to provide more affordable, high-quality, and equitable health care to employees through new purchasing and coverage models. Behavioral Health: Fragmented solutions have proven ineffective in addressing the behavioral health needs of patients. To help drive change in this area, we’re considering investment opportunities that approach patient care holistically, with behavioral and medical spend linked to create a comprehensive and unified view of the patient. Women’s Health: Despite deep investments in this area from employers, too many gaps in health and access to care still exist. There are opportunities to solve for the discrete, largely unmet, needs of women in the workforce, including but not limited to maternity, menopause, and comprehensive women’s primary care.

Digitalis Ventures engineers solutions to unmet needs in health. Our deep technical, financial, and domain expertise enables us to drive solutions across venture investing, technology development, and public-interest problem-solving. DV INVESTMENTS DV Investments provides venture capital to early-stage companies across life sciences, health technology & services, and animal health with the goal of supporting our portfolio companies throughout their development. DV PROVING GROUNDS DV Proving Grounds designs, develops, and delivers entrepreneurially-driven solutions to unmet needs in health through data science, technology development, and new ventures. DIGITALIS COMMONS Digitalis Commons is a non-profit organization affiliated with Digitalis Ventures. The Commons builds frontier-advancing, scalable solutions that have an outsized impact on important problems in health and health care.