Pivotal Life Sciences

Our mission is to serve as a catalyst for innovation by providing early-stage strategic capital and expert guidance to visionary entrepreneurs and researchers. We're committed to propelling revolutionary technologies and treatments poised to transform healthcare and significantly enhance the lives of patients and their families. About Us At Shannon Life Sciences, we are driven by a passion for innovation. We specialize in identifying and supporting early, groundbreaking ideas that have the potential to revolutionize the treatment of patients. Our team is a mosaic of experts in healthcare, finance, and entrepreneurship. This diverse expertise, coupled with a deep understanding of the healthcare sector and the intricacies of bringing novel therapies to market, positions us to help enable our portfolio companies to be successful. Our role extends beyond funding. We actively engage with academic institutions, visionary entrepreneurs, and industry leaders, forging partnerships that propel cutting-edge therapies and technologies into the healthcare arena.

When we founded the firm in 2007, our imaginations were on fire with the possibility of translating scientific discoveries to breakthrough medicines. Could we finally find cures for cancer? Would we be able to diagnose diseases before they even appear? How far could we go in restoring hope and quality of life to patients with incurable conditions? We dared to believe that nothing was impossible. To achieve what hadn’t been done before, we created a process that hadn’t been done before. By starting with big ideas and fostering collaboration among brilliant people with expertise in science, medicine, business and strategy, we set out to do more than fund startups – we aim to build sustainable, innovative companies that can transform the lives of patients. Discover Our Discovery effort is a collaborative and iterative process. We look for emerging fields of science and medicine where the time is right for us to bring transformative change to areas of unmet medical need. Working with leading scientific founders and expert advisors, we then develop a clear vision and strategy for a company with the patient front and center. With 12 years and over 50 companies worth of experience, we have created an industry-leading and differentiated approach to bring breakthrough science to patients. Launch Once a company concept has been refined and optimized through our Discovery process, we Launch the company with the necessary financial, technical and human resources to enable it to reach milestones critical for its growth and success. We become active members of the company’s leadership team, serving in interim roles to ensure the execution of the company’s R&D strategy, and to build a world-class team that shares the company’s scientific vision. Importantly, we work to establish a dynamic and innovative culture at launch where the growing team has a unified passion and commitment to make a difference in the lives of patients. Build Next, we Build on that foundation. We transition out of our interim roles and establish experienced and motivated management teams. As board members and domain experts, we work with these teams for as long as is needed to relentlessly execute on the strategy, bringing whatever resources are required from within the firm to deliver on our commitment to patients. An important element is the work we do to cultivate future partnerships and drive value creating transactions. Our companies also have access to our Beyond Great learning community, which provides peer-to-peer networking for leaders across the portfolio as well as tools and resources focused on shared elements of building successful and sustainable companies. Transform Our companies are now bringing products to patients – Transforming their lives, and the lives of their families. Third Rock portfolio companies have now launched 16 products. It is this that we are most proud of, as it means we are delivering on our mission of creating great companies that discover and develop products that make a difference for the patients we serve. Mission & Core Values Third Rock's mission is to be the preferred partner for entrepreneurs, investors, employees and industry to build great companies that discover and develop products that make a difference for the patients we serve. Integrity: always do the right thing Attitude: nothing is impossible Patients: making a difference through breakthroughs in medicine Partners: make them raving fans Organization: great people, great culture, great accomplishments Entrepreneurs: passionately innovate, found, build, have fun

Luma Group is passionately leading a transformation in healthcare, driven by a deep-seated commitment to enhance human health. We’re on a mission to turn visionary science into revolutionary healthcare solutions. Our team unites a dynamic mix of investors, scientists, clinicians, and entrepreneurs, all dedicated to advancing human health outcomes. We are not just funding remarkable scientific discoveries; we are investing in the future of humanity. Our focus is on nurturing groundbreaking innovations leveraging advanced computation and artificial intelligence that promise to redefine healthcare, ensuring that every investment we make contributes to a healthier, brighter future for all. Our approach is hands-on and collaborative, partnering with the brightest minds in science, clinical research, engineering, and entrepreneurship. We’re not just investors; we’re co-creators, working side-by-side with innovators and dreamers to transform cutting-edge scientific discoveries into groundbreaking therapeutics, diagnostics, and medical devices. Our goal is clear: to make a significant and lasting impact on human health. Every project we embark on is a step towards redefining what’s possible in healthcare, ensuring that we’re not just part of the conversation, but leading the charge in creating a healthier future for everyone.

InnoCom makes investments into worthy Life Science companies, providing: Investment opportunities in cutting edge technologies Access to early commercialization for life Science innovators Capital of $3 to 15 Million USD initial tranche for a company to complete its R&D, Preclinical & Phase I Trials; additional funding to complete Phase II Trials to take products to Licensing Industry networking to access revenue at 2-3 years following pre-clinical trials Providing revenue and/or takeout at 7 years end of clinical trials Business Counsel and advice to the company management team Corporate Officer participation, setting up strong Systems, Procedures, and Protocols Board of Directors Membership, building strong Corporate Governance Life Science Expertise, providing commercialization at the end of Preclinical and/or Clinical I & II Trials at 2-3 years Licensing Upfront Fees at 3 years, Revenue and/or Takeout at end of Clinical Trials at 7 years Enhancing the delivery of health solutions to the patients who need them

We invest in groundbreaking medicines across disease area, financing stage, and geography, with a focus on programs in, or about to enter, human trials. We are curious, rigorous, collaborative, and passionate about our work; we are also long-term investors in our team.

Harmonix invests in technological breakthroughs that will help create a future for a healthy, operational, and peaceful civilization. The fund focuses on exceptional entrepreneurs and innovative healthcare, life sciences, and deep tech companies. Harmonix is a multi-disciplinary team comprising scientists, researchers, operators, entrepreneurs, and industry experts with over 70 years of cumulative experience. Our diverse team provides founders with deep technical, operating, industry, and advisory expertise to accelerate and commercialize the next generation of technological advances. Harmonix accelerates scientific discoveries to advance human health and technology. We invest in companies that have functional solutions to real world problems. The Harmonix Process We deploy an evidence-based due diligence framework in assessing companies. Research: We identify opportunities ripe for innovation and examine areas where current standards of R&D, care, treatment, or workflow processes are inadequate. We find companies with functional solutions to problems that can create real value for stakeholders. Invest: We assess not only the technical dimensions of a venture, including supporting proof-of-concept data but also founder-fund fit. Our team looks for founders with emotional intelligence and demonstrated capacity for leadership and integrity. Accelerate: We support founders in all realms of the entrepreneurial process, including technical, operational, and business development support. We offer access to advisors who provide a level of expertise that is unavailable to many early-stage scientific companies.