Wavemaker Three-Sixty Health

We are dedicated team of experienced investors who help to enable groundbreaking work by investing in and fostering companies and technologies that advance the future of health. Entrepreneur-friendly strategic investor that speeds access to new healthcare products and services to improve patient care Established by UNC REX Healthcare in 2012 as part of its commitment to innovation Partners with emerging companies throughout North Carolina and the U.S. Leverages the talent and subject matter experts across the UNC REX and UNC Health Care network

Address the critical bottlenecks in both established and emerging markets that limit access and affordability to novel cancer solutions. Inculcate the tenets of ESG (Environmental, Social and Governance) based investing and measure the progress and impact of our portfolio using the following metrics: E: The ability to optimize differential drug and device pricing based on geography and expand access to promising products early in their lifecycle S: Ability to boost R&D productivity through operational optimization and process transformation G: Promote ethical conduct of business and collaboration while ensuring inclusion & diversity What We DoInvest in US and EU based cancer start-ups who are keen to explore emerging markets or engage in collaborative R&D. Streamline the product-market fit and ensure access to supportive infrastructure and resources. Facilitate their collaborative R&D/commercialization strategy in geographies of interest. How We Do It Accelerate the path to successful commercialization for US and EU based start-ups developing the next generation of oncology solutions by: Reducing costs through infrastructure consolidation and collaborative expertise Expanded access to capital Facilitating rapid market penetration and commercial scaling​

We’re a small team of investors, entrepreneurs, operators, clinicians, scientists and technologists, supported by our Board of healthcare and life sciences leaders and an Investment Committee of experienced venture investors and innovators. Together the partners represent one of the largest teaching hospital systems in the UK and Europe, serving a diverse local population. Their vision is to support world-leading healthcare ecosystem that drives new frontiers in modern medicine with synergistic integration of healthcare, academia, innovation and private capital.

Supporting entrepreneurs until success. Only entrepreneurs know the reality of the journey that every leader goes through before reaching success. The most experienced are therefore the best guides for those who dare to adventure. Genuine and structured experience shared alongside solid ressources to support entrepreneurs on critical issues (funding, structuring, international development, etc.) significantly change the chances of success of projects. It is with this objective in mind that 50 Partners has been developing, for the past 10 years, tailor-made and "lifelong" support programs for the best startups in the Digital, Impact and Health sectors. Beyond the Partners, we work with a whole ecosystem of investors, large groups, experts and institutions to ensure the success of these companies and the emergence of tomorrow's solutions. 50 Partners Digital Long-term, tailor-made support by entrepreneurs for entrepreneurs. Mission 50 Partners was created in 2012 with the ambition to develop the best support solution for entrepreneurs. A single organisation could be set up to bring together the best resources to focus on the selected projects. 50 outstanding entrepreneurs, founders of the most successful French companies (Blablacar, LebonCoin, Dataiku, Priceminister, ShowRoomPrivé etc.) are associated with and committed to the success of the startups. Other key resources (funding, offices, relations with key accounts, international ecosystem, etc.) are also offered to meet the needs of entrepreneurs. The particularity of this tailor-made program also lies in its lenght. Startups are provided with a long term support in order to get help at every stage of their development. To achieve this ambition, only 6 to 8 projects are selected each year out of more than 2,000. Partners The 50 Partners are the founders of the most successful French companies (Dataiku, Talentsoft, BlablaCar, LeBonCoin, etc.). They work together to select 6 to 8 promising start-ups each year to whom they provide a long term personalised support to build the most successful businesses. Each month, meetings are organised based on the issues faced by the entrepreneurs. They then share their experiences, advice and networks to answer questions and accelerate the development of projects. 50 Partners Impact A program to support the most ambitious environmental and social impact startups in France. Mission 50 Partners Impact is a startup accelerator dedicated to projects that develop innovative environmental or social solutions and provide a direct response to one or more of the Sustainable Development Goals (SDGs defined by the UN). Co-founded by 50 successful Impact entrepreneurs (Phenix, La Ruche qui dit oui, BlablaCar, Kisskissbank, Hesus...), the program offers all the necessary resources to enable projects to achieve their ambitions. Mentoring, funding, offices, network of partners (large groups, VCs, service providers), international connections etc. The support is long term in order to be able to intervene at all stages of the company's life. Each year, only 7 to 8 projects are selected from among more than 1,000 studied. Partners The 50 Partners are the founders of the most successful French impact stories (Phénix, Ynsect, BlaBlaCar, Good Goût, Castalie...). They work together to select 6 to 8 promising start-ups each year to whom they provide a long term personalised support to build the most successful businesses. Each month, meetings are organised based on the issues faced by the entrepreneurs. They then share their experiences, advice and networks to answer questions and accelerate the development of projects. 50 Partners Health Long-term support for the most ambitious health innovations by entrepreneurs, for entrepreneurs. Mission 50 Partners Health is the 50 Partners accelerator dedicated to supporting the most innovative projects in the e-health, medtech and biotech sectors. The steps to be taken to transform an innovative technology into a regulated health product, adopted by a health care system and included in a viable economic model are technical, complex and costly. Therefore, the support of an expert network significantly modifies the chances of success of a project. Co-founded by successful French healthcare entrepreneurs (Direct Medica, Lifen, Keocyt, Biocodex, Kaducéo, Domidom, SociaNova, etc.), the 50 Partners Santé program provides all the experience and business intelligence necessary to support the development of the selected projects. The particularity of this tailor-made program also lies in its lenght. Startups are provided with a long term support in order to get help at every stage of their development. Partners The 50 partners are the founders of the most successful French healthcare companies (Lifen, DirectMedica, Domidom, Biocodex, Stallergenes, etc.). They work together to select 6 to 8 promising start-ups each year to whom they provide a long term personalised support to build the most successful businesses. Each month, meetings are organised based on the issues faced by the entrepreneurs. Partners share their experience, advice and networks to answer questions and accelerate the development of projects. Ecosystem Having access to a wide network of industry professionals and business experts helps in the understanding of markets, building business relationships or gaining a better understanding of topics in business, technology or management. The "50 Friends" ecosystem is made up of more than 250 executives from large corporations, C-levels of scale-ups, investors and business experts. 50 Partners hosts meetings, workshops and individual working sessions that allow entrepreneurs to benefit from the network. Funding The definition of a good funding strategy is a key factor of success for companies. The amount, timing and investors must be thought out specifically for each project. 50 Partners ensures that 100% of the companies find the necessary funds at the different stages of their development, with the best possible investors (Business Angels and VCs). Each year, 20 to 30 fundraising operations are carried out with the support of our teams. The 50 Partners Capital Funds, subscribed by the Partners and third-party investors, can also co-invest in the projects supported. Support for fundraising. Definition of the right fundraising strategy and connections to the best investors. Access to 50 Partners Capital Funds. A short validation cycle. Bridges and co-investments. Loft 50 Partners 50 Partners offers a unique coworking space in the heart of Paris dedicated to entrepreneurs. This former factory can host up to 125 workers and is the heart of the ecosystem (workshops, conferences, networking, etc.). The projects supported benefit from free hosting. The loft also welcomes entrepreneurs in coworking with a flexible and non-binding office offer. For all office requests or event space reservations, contact leloft@50partners.fr Community 50 Partners brings together more than 300 entrepreneurs (Partners and alumni) in France and abroad. This unique, experienced and caring community is an extraordinary resource for entrepreneurs. Numerous events are organized to enable this exchange between all the founders: workshops, dinners, green days, conferences, etc. Finally, annual events such as the"50 Day 2023" or"Impact & Innovation Days 2022", a unique conference to discover tomorrow's solutions for the Environment and Society. International 50 Partners develops relationships with ecosystems around the world. Regular study trips to the US, Asia, and all over Europe allow us to build relationships with entrepreneurs, investors, large companies and all those who make innovation happen internationally. A network of international accelerators offers the opportunity for startups in the program to be hosted on site to study possible extensions in promising new markets. Finally, many Partners who have successfully developed their activities abroad, advise entrepreneurs as they embark on this key stage.

Headquartered in Silicon Valley, H7 BioCapital is a global venture platform that supports the transformational growth of healthcare companies through its influential venture capital financing, global accelerator program, venture club, VC class, webinars, conferences and other strategic events, and connect them with investors, scientists, physicians, corporate partners and other industrial professionals to jointly build a resource - rich healthcare innovation ecosystem. H7 BioCapital consists of three parts of organizations: H7 Accelerator, H7 Venture, and H7 Café to support the transformational growth of healthcare by striving to be transformational itself. Need a boost with your healthcare startup? Let H7 be your support - Health, Heal, Happiness, Hope, Humanity, Home and Holistic! H7 Accelerator 3-month-long cohort-based healthcare accelerator program providing mentorship, funding and other support to early-stage biotech, medtech and device startups along with a lifelong network for these leaders and innovators. H7 Venture Investment platform providing early stage funding support to healthcare startups that are believed to have a long-term growth potential. H7 Café A high-quality startup community that supports the growth of healthcare entrepreneurs by frequent events such as networking, educational workshop, private deal flow meetings and other programs to connect the corporate, scientists, investor and founder ecosystem.

BrightEdge propels groundbreaking patient-centric solutions by investing in and supporting the most innovative startup companies to advance science, reduce disparities, and promote healthcare sustainability. BrightEdge is the innovation, impact investment, and venture capital arm of the American Cancer Society (ACS). Through our donor-funded ACS Impact Venture Fund (AIVF), we further ACS’s mission by investing in for-profit, early-stage companies developing cutting-edge, cancer-focused therapeutics, diagnostics, devices, and technologies to fuel and accelerate our vision of ending cancer as we know it, for everyone. About BrightEdge and The American Cancer Society BrightEdge is helping create a stream of alternate income to sustain the critical work being done across our pillars. Donations to BrightEdge become a sustainable source of financial support to the American Cancer Society, diversifying and modernizing the ACS’s income sources. Investment returns from the AIVF portfolio are both reinvested in AIVF to further support new and existing companies in the portfolio and additional proceeds are used to sustain ACS’s lifesaving programs in research, access, and health equity. BrightEdge investment decisions and innovation programming are guided by the mission priorities of ACS and seek to achieve mission-driven social impact through its proprietary Cancer Impact Investment FrameworkTM (CIIFTM). BrightEdge builds on the American Cancer Society’s commitment to funding and conducting cancer research and plays a key role in accelerating today’s most promising oncology-focused technologies. Our ability to translate scientific discoveries into accessible cures and solutions depends on investments in entrepreneurial for-profit companies that can validate, develop, and commercialize products and services at scale in the healthcare marketplace for people facing cancer. BrightEdge plays a unique role alongside traditional venture capital firms by addressing early-stage funding gaps, incubating high-impact companies, bringing system-level knowledge to companies at critical points in product development, and helping emerging companies access world-class intellectual and human capital as they grow. Learn how BrightEdge will help improve 1.5 million lives by investing in cancer-focused therapies and technologies in its most recent annual report and infographic.